CELLIVERY

R&D

PUBLICATION

"Founder’s Publication as the Corresponding Author (2011 ~ )"

01 E. Chung, Y. Choi, J. Park, W. Nah, J. Park, Y. Jung, J. Lee, H. Lee, S. Park, S. Hwang, S. Kim, J. Lee, D. Min, J. Jo, S. Kang, M. Jung, P. H. Lee, H. E. Ruley, D. Jo (2020) Intracellular delivery of Parkin rescues neurons from accumulation of damaged mitochondria and pathological α-synuclein, Sci. Adv, 2020;6: eaba1193, 29 April 2020
02 Duong T, Kim J, Ruley HE and Jo D (2014) Cell-permeable parkin proteins suppress parkinson disease- associated phenotypes in cultured cells and animals, PLoS ONE, 2014 Dec 17;9(12):e116242.
03 Lim J*, Kim J*, Kan g J and Jo D (2014) Partial somatic to stem cell transformations with cell- permeable reprogramming factors, Scientific Reports, 2014 Mar 12;4:4361-4371.
04 Lim J*, Duong T*, Lee G, Seong BL, El-Rifai W, Ruley HE and Jo D (2013) The effect of intracellular protein delivery on the anti-tumor activity of recombinant human endostatin, Biomaterials, 2013 Aug 1;34(26): 6261-71. Epub 2013 May 25.
05 Lim J, Duong T, Do N, Do P, Kim J, Kim H, El-Rifai W, Ruley HE and Jo D (2012) Antitumor activity of cell-permeable RUNX3 protein in gastric cancer cells, Clinical Cancer Research, 2013 Feb 1;19(3):680-690. Epub 2012 Dec 10.
06 Lim J, Kim J, Duong T, Lee G, Kim J, Yoon J, Kim J, Kim H, Ruley HE, El-Rifai W and Jo D (2012) Antitumor activity of cell- permeable p18INK4c with enhanced membrane and tissue penetration. Molecular Therapy, 2012 Aug;20(8):1540-1549. Epub 2012 May 22.
07 Lim J, Jang G, Kang S, Lee G, Nga DT, Phuong DT, Kim H, El-Rifai W, Ruley HE and Jo D (2011) Cell permeable NM23 blocks the maintenance and progression of established pulmonary metastasis. Cancer Research, 2011 Dec 1;71(23):7216-25. Epub 2011 Oct 10.

"Founder’s Publication as the First or Co-Author (2001 ~ )"

01 Ock S, Ahn J, Lee SH, Kang H, Offermanns S, Ahn HY, Jo YS, Shong M, Cho BY, Jo D, Abel ED, Lee TJ, Park WJ, Lee IK, Kim J (2013) IGF-1 receptor deficiency in thyrocytes impairs thyroid hormone secretion and completely inhibits TSH-stimulated goiter, FASEB Journal, 2013 Dec;27(12):4899-4908. Epub 2013 Aug 27.
02 Jeon D, Kim S, Chetana M, Jo D, Ruley HE, Lin SY, Rabah D, Kinet JP, Shin HS (2010) Observational fear learning involves affective pain system and Cav1.2 Ca2+ channels in ACC, Nature Neuroscience, 2010 Apr;13(4):482-8. Epub 2010 Feb 28.
03 Kee H, Eom G, Joung H, Shin S, Kim J, Cho Y, Choe N, Sim B, Jo D, Jeong M, Kim K, Seo J, Kook H (2008) Activation of histone deacetylase2 by inducible Hsp70 in cardiac hypertrophy. Circulation Research, 2008 Nov 21;103(11):1259-69. Epub 2008 Oct 10.
04 Lin Q, Jo D, Gebre-Amlak KD and Ruley HE (2004) Enhanced cell-permeant Cre protein for site-specific recombination in cultured cells. BMC Biotechnology, 2004 Oct 22;4(25):1-13
05 Jo D, Liu D, Yao S, Collins RD and Hawiger J (2005) Intracellular protein therapy with SOCS3 inhibits inflammation and apoptosis. Nature Medicine, 2005 Aug;11(8):892-8. Epub 2005 Jul 10.
06 Jo D, Leren T, Yang Z, Chung Y, Taylor JM and Paik YK (1995) Characterization of an upstream regulatory element of the human apolipoprotein E gene, and purification of its binding protein from the human placenta. Journal of Biochemistry, 1995 Apr;117(4):915-22.
07 Jo D, Lin Q, Nashabi A, May D, Unutmaz D, Pietenpol JA and Ruley HE (2003) Cell cycle-dependent transduction of cell-permeant Cre recombinase proteins. Journal of Cellular Biochemistry, 89(4):674-687
08 Jo D, Nashabi A, Doxsee D, Lin Q, Unutmaz D, Chen J and Ruley HE (2001) Epigenetic regulation of gene structure and function with a cell permeable Cre recombinase. Nature Biotechnology, 19(10):929-933

"Selected Publications of Dr. Ruley"

01 Ruley HE, 1983, Adenovirus early region 1A enables viral and cellular transforming genes to transform primary cells in culture. Nature, (5927)304: p. 602-6
02 Ruley HE and, Fried M, 1983, Clustered illegitimate recombination events in mammalian cells involving very short sequence homologies. Nature, (5922)304: p. 181-4
03 Cook JL and Ruley HE, et al., 1986, Expression of the adenovirus E1A oncogene during cell transformation is sufficient to induce susceptibility to lysis by host inflammatory cells. Proc Natl Acad Sci U S A, (18)83: p. 6965-9
04 Franza BR, Jr. and Ruley HE, et al., 1986, In vitro establishment is not a sufficient prerequisite for transformation by activated ras oncogenes. Cell, (3)44: p. 409-18
05 Hirakawa T and Ruley HE, et al., 1988, Rescue of cells from ras oncogene-induced growth arrest by a second, complementing, oncogene. Proc Natl Acad Sci U S A, (5)85: p. 1519-23
06 Von Melchner H and Ruley HE, et al., 1990, Isolation of cellular promoters by using a retrovirus promoter trap. Proc Natl Acad Sci U S A, (10)87: p. 3733-7
07 Reddy S and Ruley HE, et al., 1992, Fluorescence-activated sorting of totipotent embryonic stem cells expressing developmentally regulated lacZ fusion genes. Proc Natl Acad Sci U S A, (15)89: p. 6721-5
08 Von Melchner H and Ruley HE, et al., 1992, Selective disruption of genes expressed in totipotent embryonal stem cells. Genes Dev, (6)6: p. 919-27
09 Lowe SW and Ruley HE, et al., 1993, Stabilization of the p53 tumor suppressor is induced by adenovirus 5 E1A and accompanies apoptosis. Genes Dev, (4)7: p. 535-45
10 DeGregori J and Ruley HE, et al., 1994, A murine homolog of the yeast RNA1 gene is required for postimplantation development. Genes Dev, (3)8: p. 265-76
11 Lowe SW and Ruley HE, et al., 1994, Abrogation of oncogene-associated apoptosis allows transformation of p53-deficient cells. Proc Natl Acad Sci U S A, (6)91: p. 2026-30
12 Martin WD Ruley HE, et al., 1996, H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection. Cell, (4)84: p. 543-50
13 Hicks GG and Ruley HE, et al., 1997, Functional genomics in mice by tagged sequence mutagenesis. Nat Genet, (4)16: p. 338-44
14 Hicks GG and Ruley HE, et al., 2000, Fus deficiency in mice results in defective B-lymphocyte development and activation, high levels of chromosomal instability and perinatal death. Nat Genet, (2)24: p. 175-9
15 Jo D and Ruley HE, et al., 2001, Epigenetic regulation of gene structure and function with a cell-permeable Cre recombinase. Nat Biotechnol, (10)19: p. 929-33
16 Osipovich AB and Ruley HE, et al., 2005, Post-entrapment genome engineering: first exon size does not affect the expression of fusion transcripts generated by gene entrapment. Genome Res, (3)15: p. 428-35
17 Donahue SL and Ruley HE, et al., 2006, Carcinogens induce genome-wide loss of heterozygosity in normal stem cells without persistent chromosomal instability. Proc Natl Acad Sci U S A, (31)103: p. 11642-6
18 Osipovich AB and Ruley HE, et al., ., 2008, Dyggve-Melchior-Clausen syndrome: chondrodysplasia resulting from defects in intracellular vesicle traffic. Proc Natl Acad Sci U S A, (42)105: p. 16171-6